The course focuses on the physical processes related to blood flow, measuring hemodynamic parameters in vivo and properties of blood vessels. Special attention will be given to artificial capillary systems and their application in treatment of renal or lung insuficiency. Further properties of human tissue and body fluids will be discussed, including methods of measurement. Students will also learn about the measurement of fundamental physiological variables. This knowledge will be complemented with the basics of electrochemistry, optics and acoustics, always in relation to the human body and in biological systems. Theoretical knowledge will be complemented by practical experience in laboratories.
Assessment: attendance and activity during exercises.
Examination: Knowledge of material from lectures and exercises.
Acquaint students with basic physiological principles in terms of physical laws.
2. Hemodynamics I - characteristics of ideal fluid properties and composition of blood flow and blood distribution, properties of the heart and arteries
3. Hemodynamics II - blood pressure measurement, descriptions and examples of automatic electronic tonometer, new methods of blood pressure measurement
4. Hemodynamics III - blood flow measurement
5. Hemodynamics IV - extracorporeal circulation and compensation hearts
6. The properties of the tissue and its interaction with the technical equipment - Electromagnetic spectrum, basic properties of tissues, effects of electromagnetic fields on human tissue
7. The exchange of gases - breathing physiology, spirometry, pulse oximetry
8. Measuring temperature in health care - basic units and definitions, measurement fluidic conventional thermometers, measuring IR thermometers - practical demonstrations, black body radiation, temperature measurement with digital thermometers, Legislation and metrology
9. Ionizing radiation - detectors ionizing radiation dosimetry
10. The engines used in healthcare - basic engine types and their properties, examples of applications in healthcare
11. Acoustics - sound level meters: principle of function and their validation, basic definitions, sound pressure gauges, audiometry, otoacoustic emissions, cochlear neuroprostheses
12. Optics - basic definition, eye anatomy and physiology of vision, LASER eye surgery
13. Plasma medicine - basic definition, plasma sterilisation, plasma arc
14. Excursion to professional workplace
1. Physical units in medicine, measurement uncertainty
2. Measuring blood pressure - a demonstration auscultation and oscillometric methods, validation of automated electronic tonometer
3. Vital functions monitors - measurement of basic vital functions of the simulator of physiological parameters. AED.
4. Peristaltic pump - peristaltic pump calibration
5. Breathing - the implementation of resting and stress measurement, evaluation of measurements, measuring the concentration of oxygen in the exhaled air, the implementation of resting and stress measurement, validation pulse oximeters tester pulse oximeters
6. Excursion to the workplace Cardiovascular mechanics, Faculty of Mechanical Engineering, CTU in Prague
7. The first test
8. Lecher lines - measuring basic characteristics of Lecher lines
9. Measurement of solution properties - conductivity, pH, density, the viscosity of liquids
10. RF ablation (ESU) - ESU power measurement, recording during RF signal when cut and coagulation
11. Engines - measuring characteristics of engines
12. Acoustics - measurement volume levels in different modes sound meter, sound level meter calibration
13. Dielectric heating - standing waves, power control magnetron efficiency of heating water in a microwave oven.
14. The second test
1. Vander A. J. and col.: Human Physiology, McGraw-Hill Company, Sydney, 1986
2. Bentley J. P.: Principles of Measurement Systems, Logman Scientific and Technical, London 1993
3. Webster, J. G.: Medical instrumentation: Application and design, 4th edition, Wiley 2009
4. Webster, J. G.: The Physiological Measurement Handbook, CRC Press 2015